Effect of synthetic hormone, 17α-ethinylestradiol on hematological and biochemical parameters in fish Channa punctatus (Bloch.1793)

Environmental Protection includes programs that are aimed to reducing risks the environment from hazardous materials and chemical wastes. Nowadays, 17α-ethinylestradiol, a synthetic estrogen, has become one of most commonly used active ingredients for oral contraception, interfere with normal functioning endocrine systems, thus affecting reproduction development in wildlife. The fresh water food fish, Channa punctatus, was selected as test animal perform desired experimental work. physio-chemical parameters (Temperature, pH, DO, CO2, Hardness) medium, hematological (WBC, RBC, Hb, PCV, MCV, MCH, Platelet) biochemical (Total protein, AST, ALT, ALP, Urea Creatinine) fish were analysed. punctatus exposed three different concentrations 17α-ethinylestradiol (5, 10 20 ng/L), along control group 28 days their samples collected at an interval 7, 14, 21 days. Result shows parameters- MCH Platelet found significantly decreased WBC increased ALP while, Total protein Creatinine showed insignificant differences on exposure 17α-ethinylestradiol. Therefore, study stated produce adverse effect parameter which might affect physiology immunity fish.